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Meaning of homeostasis, osmoregulation in plants and animals, the human kidney and urine formation, kidney disorders and treatment, the skin and its role in temperature control, and thermoregulation in humans.
Homeostasis is the maintenance of a steady internal environment in the body despite changes outside it. Body temperature, water content, salt level, blood glucose and pH are kept within narrow limits because enzymes and cells work properly only under such conditions. Most systems work by negative feedback: a change is detected, and the body responds in a way that reverses the change.
Osmoregulation is the control of water and salt balance in the body fluids. The water potential of body fluids must stay steady, otherwise cells shrink or swell. The kidneys, skin and lungs all help to control the balance between water gained and water lost.
Osmoregulation in plants is related to their habitat:
Osmoregulation in animals differs by environment. Freshwater animals take in water by osmosis and pass out a large volume of dilute urine. Marine bony fish lose water by osmosis, so they drink sea water and remove extra salt through the gills. Desert animals such as the camel save water by passing very concentrated urine and sweating little.
Excretion is the removal of metabolic waste products from the body. The main excretory organs of humans are the kidneys, which remove urea, extra water and salts. The lungs remove carbon dioxide and water vapour, and the skin removes water, salts and a little urea in sweat. Urea is made in the liver from the breakdown of excess amino acids.
The urinary system consists of two kidneys, two ureters, one urinary bladder and one urethra. Each kidney is bean shaped and lies on either side of the backbone below the ribs. In section it shows an outer cortex, an inner medulla and a central pelvis that leads into the ureter. Urine passes down the ureter to the bladder, where it is stored until it leaves through the urethra.
The nephron is the structural and functional unit of the kidney. Each kidney has about one million nephrons. Its parts are:
Urine is formed in three steps:
Urine is about 95 percent water. It also contains urea, uric acid, creatinine and salts. The amount of water in urine is controlled by antidiuretic hormone (ADH) from the pituitary gland. When the body is short of water, more ADH is released, the collecting ducts reabsorb more water, and a small volume of concentrated urine is passed. When there is excess water, less ADH is released and dilute urine is passed in large amount.
Common kidney problems include kidney stones and kidney failure. Kidney stones form when salts such as calcium oxalate crystallise in the kidney, and they cause severe pain. Small stones pass out with urine, while larger ones are broken by ultrasound waves (lithotripsy) or removed by surgery. Kidney failure is treated by dialysis, in which an artificial kidney machine removes urea from the blood, or by a kidney transplant from a matching donor.
The skin is the largest organ of the body and helps in homeostasis. It has an outer epidermis and an inner dermis with sweat glands, sebaceous glands, hair follicles, blood vessels and nerve endings. It protects the body, senses touch, pain and temperature, makes vitamin D in sunlight, and controls body temperature.
Thermoregulation is the control of body temperature at about 37 °C, and it is directed by the hypothalamus in the brain:
Study tip: Practise labelling the nephron and a section of the kidney, since diagrams carry marks. Learn the three steps of urine formation in order, and write temperature control answers as a chain: stimulus, hypothalamus, response, result.
Say the meaning first, then open the card to check.
Maintenance of a constant internal environment in the body.
Control of the water and salt content of body fluids.
Removal of metabolic waste products from the body.
Structural and functional unit of the kidney.
Filtration of blood under high pressure in the glomerulus.
Return of useful substances from the kidney tubule to the blood.
Removal of wastes from the blood of a patient using an artificial kidney.
Widening of skin arterioles so that more heat is lost.
Hormone that makes the collecting duct reabsorb more water.
These are the kind of questions asked for 2, 3 and 5 marks. Try each one before opening the answer.
Homeostasis is the maintenance of a constant internal environment in the body. Examples are control of body temperature at about 37 °C and control of the water content of blood.
The steps are ultrafiltration in the glomerulus, selective reabsorption mainly in the proximal tubule, and tubular secretion.
Xerophytes live in dry places. They have a thick waxy cuticle, sunken stomata, small or spiny leaves and long roots. These features reduce transpiration and help them absorb as much water as possible.
When the blood becomes too concentrated, the pituitary gland releases more ADH. ADH makes the collecting ducts more permeable, so more water is reabsorbed into the blood. A small volume of concentrated urine is passed. When the blood has too much water, less ADH is released, less water is reabsorbed, and a large volume of dilute urine is passed. In this way the water content stays near normal.
The hypothalamus detects the rise in temperature. Sweat glands produce more sweat, and the evaporation of sweat takes heat from the skin. Arterioles in the skin widen, so more blood flows near the surface and more heat is radiated. These changes bring the temperature back to about 37 °C.
A nephron begins with Bowman's capsule, a cup that surrounds a knot of capillaries called the glomerulus. It continues as the proximal convoluted tubule, then the U shaped loop of Henle that dips into the medulla, and then the distal convoluted tubule. Many nephrons join a collecting duct, which carries urine to the pelvis of the kidney.