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Unit GIC2 · Element 7: Chemical and Biological Agents
7.1 Hazardous Substances
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Health hazard classification

Chemicals that are hazardous to health are placed in these hazard classes.

Hazard classGeneral description
Acute toxicityAdverse effects of a substance that result from a single exposure, or from several exposures in a short period (usually under 24 hours). Exposure can be oral, dermal or by inhalation.
Skin corrosion and irritationCorrosion is irreversible damage to the skin. Irritation covers products that cause reversible damage, such as redness or inflammation, after exposure.
Serious eye damage and eye irritationSerious damage is tissue damage or physical decay of vision that is not fully reversible. Irritation covers products that cause reversible effects, normally within 21 days of exposure.
Respiratory or skin sensitisationA respiratory sensitiser is a chemical that leads to hypersensitivity of the airways after inhalation. A skin sensitiser leads to an allergic response after skin contact.
Germ cell mutagenicityChemicals that may cause mutations in human germ cells that can be passed on to offspring.
CarcinogenicityA carcinogen is a substance or mixture that induces cancer or increases its incidence.
Reproductive toxicityAdverse effects on sexual function and fertility in adult males and females, and on the development of offspring.
Specific target organ toxicity, single or repeated exposureProducts that cause or may cause damage to organs such as the liver, kidneys or blood after a single or prolonged or repeated exposure.
Aspiration hazardAspiration is the entry of a liquid or solid chemical into the trachea and lower respiratory system, directly through the mouth or nose or indirectly from vomiting. Aspiration toxicity includes severe acute effects such as chemical pneumonia, varying degrees of lung injury, or death.
Page 2 of 14 in this chapter · page 26 of 88 in the book

Summary notes for Element 7 · Cheat sheet · Glossary. A study aid, not published or endorsed by NEBOSH.

Written by Imran Qureshi (NEBOSH)